Adaptil is a synthetic copy of the natural canine-appeasing pheromone that has been proven to help support dogs in a range of stressful situations. It is odorless, non-sedative, non-systemic, and can be used alongside all other types of medication. The spray can be applied directly on bedding, inside crates, indoor kennels, or in the car. It is a convenient formulation for intermittent use. Effects should last approximately 4-5 hours, although each animal will respond differently. Should not be directly sprayed on the animal or near the animal's face.